Test Directory

This test is used to rule out the presence of maternal cell contamination within a fetal specimen to aid in the accurate interpretation of prenatal molecular genetic or cytogenetic results.

Specimen Type: Whole Blood

Collection Container: Pale Yellow Top (ACD, Solution A)

Alternate Collection Container: Lavender Top (EDTA), Pink Top (EDTA), or Oragene Dx saliva kit

Desired Specimen Volume: 8.5 mL

1. Collect a pale-yellow top (ACD Solution A) tube via venipuncture.

*For saliva samples, follow the instructions provided in the kit.

**Requires Integrated Genetics Test Requisition**

1. Transport 8.5 mL of whole blood in the original collection container.
2. Maternal samples sent for maternal cell contamination studies should be submitted under a separate requisition from fetal specimens (CVS or amniotic fluid).

For saliva samples do not eat, drink, smoke or chew gum 30 minutes prior to collection.

Transport to the laboratory at room temperature.  

• Hemolysis

See patient report.

False positive or negative results may occur for reasons that include genetic variants, blood transfusions, bone marrow transplantation, or erroneous characterization of family relationships. Molecular-based testing is highly accurate, but as in any laboratory test, rare diagnostic errors may occur. Results are provided for identification of maternal cell contamination in the specimen itself, and not for diagnostic purposes.