Test Directory

• hCG Value
• hCG MoM
• uE3 Value
• DIA MoM
• DSR (By Age) 1 IN
• AFP Value
• T18 Risk
• T18 (By Age)
• DSR (Second Trimester) 1 IN
• AFP MoM
• uE3 MoM
• DIA Value
• OSBR Risk 1 IN
• Interpretation

Screening test for open neural tube defects (detects 80% open spina bifida, 90% anencephaly), Down syndrome (detects 75% to 80%), and trisomy 18 (detects 73%).

Specimen Type: Serum

Collection Container: Gold Top, Serum Separator

Desired Specimen Volume: 5 mL

1. Collect a gold top, serum separator tube via venipuncture
   • Down syndrome screening is offered for gestational ages 15.0 to 21.9 weeks. Open spina bifida screening is offered for gestational ages 15.0 to 23.9 weeks. The optimal gestational age for open spina bifida screening is 16.0 to 18.9 weeks.

1. Allow blood to clot, avoiding hemolysis. 
2. Separate serum from cells.
3. Transport 5 mL of serum in the original collection container. Do not aliquot. Pour-off is not advised. 

• Maternal serum specimens must be drawn prior to amniocentesis to avoid contamination with fetal blood.
• Down syndrome screening is offered for gestational ages 15.0 to 21.9 weeks. Open spina bifida screening is offered for gestational ages 15.0 to 23.9 weeks. The optimal gestational age for open spina bifida screening is 16.0 to 18.9 weeks.

Transport to the laboratory refrigerated. 

• Gross hemolysis
• Gross lipemia
• Quantity not sufficient for analysis
• Improper specimen type

 See patient report.

AFP tetra is a screening test. A positive AFP tetra result means that more diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present.

• AFP Tetra
• Alpha-Fetoprotein (AFP) Tetra Profile