Test Directory

• Down Syndrome
• Down Syndrome Interpretation
• Trisomy 18
• Trisomy 18 Interpretation
• hCG Value
• hCG MoM
• PAPP-A MoM
• PAPP-A Value

Screening test for open neural tube defects, Down syndrome, and trisomy 18.

Specimen Type: Serum

Collection Container: Gold Top, Serum Separator

Desired Specimen Volume: 3 mL

1. Serum testing is provided from 10.0 to 14.0 weeks of gestation. NT can be assessed when the CRL is 45 to 84 mm.
2. Collect a gold top, serum separator tube via venipuncture.

1. Allow blood to clot, avoiding hemolysis.
2. Separate serum from cells.
3. Transport 3 mL of serum in the original collection container. Do not aliquot.
4. Pour-off is not advised.

Serum testing is provided from 10.0 to 14.0 weeks of gestation. NT can be assessed when the CRL is 45 to 84 mm.

Maternal serum specimens must be drawn prior to amniocentesis to avoid contamination with fetal blood.

Transport to the laboratory refrigerated. 

• Gross hemolysis
• Gross lipemia
• Quantity not sufficient for analysis
• Improper specimen type

 See patient report.

Sequential screening requires two specimens: one collected in the first trimester and one in the second trimester. This test number is for the first trimester portion of the test. Result interpretation for the first trimester portion will be provided only for screen-positive specimens. Result interpretation for all others will be provided only when the second trimester specimen is received and tested. This is a screening test. A positive result means that diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present.

• Down Syndrome
• Nuchal Translucency (NT)
• PAPP-A