Test Directory

• PAPP-A Value
• PAPP-A MoM
• AFP MoM
• AFP Value
• Trisomy 18
• Trisomy 18 Interpretation
• Nuchal Translucency MoM
• uE3 Value
• uE3 MoM
• OSB Interpretation
• Down Syndrome Interpretation
• hCG Value
• hCG MoM
• DIA Value

Screening test for open neural tube defects, Down syndrome, and trisomy 18.

Specimen Type: Serum

Collection Container: Gold Top, Serum Separator

Desired Specimen Volume: 5 mL

1. Patient must have submitted a previous specimen in the first trimester for the Sequential 1 test.
2. Collect a gold top, serum separator tube via venipuncture.

1. Allow blood to clot, avoiding hemolysis.
2. Separate serum from cells.
3. Transport 5 mL of serum in the original collection container.
4. Do not aliquot. Pour-off is not advised

• Testing is provided from 15.0 to 21.9 weeks of gestation.
• Maternal serum specimens must be drawn prior to amniocentesis to avoid contamination with fetal blood.

Transport to the laboratory refrigerated. 

• Gross hemolysis
• Gross lipemia
• Quantity not sufficient for analysis
• Improper specimen type

 See patient report.

Sequential screening requires two specimens: one collected in the first trimester and one in the second trimester. This test number is for the second trimester portion of the test. This is a screening test. A positive result means that diagnostic testing may be offered to the pregnant woman to determine if a neural tube defect or chromosome abnormality is present.

• AFP, Maternal
• Down Syndrome