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Test Code
MEPCR
Test Name
Meningitis/Encephalitis, CSF, PCR, 14 Targets
CPT Codes
87483
Included Tests

Bacteria

  • E. coli K1
  • H. influenzae
  • L. monocytogenes
  • N. meningitidis
  • S. agalactiae
  • S. pneumoniae

Viruses

  • Cytomegalovirus
  • Enterovirus
  • Herpes simplex 1
  • Herpes simplex 2
  • Human Herpes Virus 6 (HHV6)
  • Parechovirus
  • Varicella Zoster Virus

Yeast

  • C. neoformans/gattii
Expected Turnaround Time
1 - 4 hours
Clinical Utility
This assay can rapidly detect and differentiate 14 of the most common pathogens implicated in meningitis and/or encephalitis.
Specimen and Container Info

Specimen: Cerebrospinal Fluid

Collection Container: Sterile, Non-additive Container (CSF)

Desired Volume: 1 mL

Minimum Acceptable Volume: 0.5 mL
Processing and Submission Instructions

Concomitant CSF culture is warranted for the recovery of off panel targets and for subsequent susceptibility testing of any bacterial pathogens to aid treatment decisions.
Transport Instructions

 Transport to the laboratory at room temperature.

Stability Requirements

Room Temperature

 24 hours

Refrigerated

7 days
Methodology
Multiplex Polymerase Chain Reaction (PCR)
Reference Intervals

 Not Detected
Limitations
  • This assay is not intended for use with CSF collected from indwelling medical devices.
  • For patients with specific risk factors for cryptococcal meningitis, the Cryptococcal Antigen (CRYPC) test is more sensitive option and should be considered if clinically warranted in the event the results of the panel are negative.
Performing Location
Roble Road Core Laboratory
Alternate Names
  • Meningitis Panel
  • Encephalitis Panel
  • CSF PCR
  • Spinal Fluid Multiplex Panel
Testing Schedule
Routine, daily
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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