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Test Code
MFURA
Test Name
Metanephrines, Pheochromocyt
CPT Codes
82570, 83835
Included Tests
  • Creatinine
  • Normetanephrine
  • Metanephrine
  • Metanephrine/Creatinine ratio
Expected Turnaround Time
3 - 7 days
Clinical Utility

Diagnose the presence of a pheochromocytoma, neuroblastoma, and ganglioneuroblastoma.
Specimen and Container Info

Specimen Type: Random Urine

Collection Container: Plastic Urine Container (Preservative Free)   

Desired Specimen Volume: 10 mL
Collection Instructions
  1. Collect first morning urine in a plastic urine container (preservative free).
Processing and Submission Instructions
  1. Transport 10 mL of urine in the original collection container or transfer to clear aliquot tubes (screw cap).
Patient Preparation

Medication and dietary monitoring. A number of drugs act through catecholamine mechanisms and must be discontinued 72 hours before and during collection. Bananas, pineapple, and plums are contraindicated.
Transport Instructions

Transport to the laboratory refrigerated. 
Stability Requirements

Room Temperature

7 days

Refrigerated

14 days

Frozen

14 days
Methodology
Liquid Chromatography - Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

See patient report.
Limitations

Simultaneous measurement of urine creatinine permits expression of the metanephrine:creatinine ratio. Some clinicians use >2.2 μg metanephrines/mg creatinine to distinguish pheochromocytoma from normal with this ratio.
Alternate Names
  • Metanephrines, Pheochromocytoma Evaluation
  • Metanephrines, Random Urine
  • Pheochromocytoma Evaluation
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Varies
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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