Test Directory

Test Code
MTHA
Test Name
Methadone, Qualitative, Pain Management, Urine
CPT Codes
80307
Expected Turnaround Time
1 - 5 days (for confirmation of positive screening results or if reflex testing is required)
Clinical Utility
  • Compliance monitoring for pain management.
  • Useful for the detection of methadone in urine.
  • This is a presumptive test with conditional definitive testing of positive and unexpected negative presumptive results.
  • This test includes medication match analysis.
  • Direct definitive testing is available.
Specimen and Container Info

Preferred Specimen Type: Urine

Preferred Collection Container: Plastic Urine Container (Preservative Free)

Desired Specimen Volume: 10 mL

Processing and Submission Instructions
  • If using paper requisition, submit specimen with a completed Pain Management Drug Testing Request (HNL-56).
  • Interpretation is dependent on completing the prescribed medication history section at the bottom of the form.
  • List only the medications taken within the last 2-3 days.
Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Room Temperature

 7 Days

Refrigerated

 7 Days

Causes for Rejection

Urine specimens received in tubes containing preservatives will be rejected.

Methodology
Enzyme Immunoassay (EIA)
Reference Intervals

Interpretation and concentration of drug/metabolite in urine is dependent on dose, time of dose, metabolic rate, and hydration state.

Limitations

Class

Cutoff Concentration (ng/mL)

Methadone

300

Performing Location
Roble Road Core Laboratory
Alternate Names
  • Dolophine
  • Methadose
Testing Schedule
Routine, daily