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Test Code
MMA
Test Name
Methylmalonic Acid
CPT Codes
83921
Expected Turnaround Time
3 - 6 days
Clinical Utility

Serum methylmalonic acid (MMA) measurement is used to evaluate individuals with signs and symptoms associated with vitamin B12 deficiency1-7 or congenital methylmalonic academia.
Specimen and Container Info

Specimen Type: Serum

Alternate Specimen Type: Plasma

 

Collection Container: Red Top, Plain or Gold Top, Serum Separator 

Alternate Collection Container: Green Top (Sodium or Lithium Heparin)

 

Desired Specimen Volume: 2 mL 
Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.  
Processing and Submission Instructions
  1. Separate serum from cells within one hour of collection.
  2. Transfer 2 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated. 
Stability Requirements

Room Temperature

 14 days

Refrigerated

14 days

Frozen

19 days

Freeze/Thaw Cycles

 Stable x3
Causes for Rejection
  • Plasma from a light blue-top or yellow-top tube
Methodology
Liquid Chromatography - Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

See patient report.

Reference Lab
Labcorp Of America Holdings
Testing Schedule
Monday-Friday
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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