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Test Code
NMOIG
Test Name
NMO IgG Autoantibodies
CPT Codes
86051
Expected Turnaround Time
3 - 5 days
Clinical Utility

Establishing the diagnosis of neuromyelitis optica (NMO) and related disorders, including relapsing transverse myelitis or relapsing optic neuritis. Distinguishing NMO and NMO spectrum disorders from multiple sclerosis early in the course of disease. This test can also be used to trigger initiation and monitor effectiveness of therapy.
Specimen and Container Info

Specimen Type: Serum


Collection Container: Gold Top, Serum Separator 

Alternate Collection Container: Red Top, Plain

 

Desired Specimen Volume: 0.2 mL
Collection Instructions
  1. Collect gold top serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 0.2 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated. 
Stability Requirements

Room Temperature

24 hours

Refrigerated

14 days

Frozen

14 days

Freeze/Thaw Cycles

Stable x3
Methodology
ELISA
Reference Intervals

See patient report.
Limitations

Seronegativity does not exclude the diagnosis of NMO.1 Immunosuppressive therapy may result in negative results.
Alternate Names
  • Aquaporin-4
  • NMO IgG
  • Neuromyelitis Optica, IgG Autoantibodies
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, 3 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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