Test Directory

Test Code
NORVS
Test Name
Norovirus 1/2, PCR
CPT Codes
87798 X 2
Included Tests
  • Norovirus 1, PCR
  • Norovirus 2, PCR
Expected Turnaround Time
2 - 5 days
Clinical Utility

Diagnosing gastrointestinal disease (diarrhea or voimiting) caused by norovirus genogroups 1 and 2. This test should not be used as a test-of-cure.

Specimen and Container Info

Specimen Type: Stool

Collection Container: Para-Pak Culture and Sensitivity Media, Cary-Blair

Desired Specimen Volume: 1 g

Collection Instructions

Stool must remain at room temperature. Do not store refrigerated of frozen.

  1. Collect stool in a plastic sterile container.
Processing and Submission Instructions
  1. Transfer 1g of stool to a Para-Pak Culture and Sensitivity Media vial within 1 hour of collection.
  2. Visibly formed feces are not consistent with Norovirus gastrointestinal disease and should not be submitted for testing.
Transport Instructions

Transport to the laboratory at room temperature.  

Stability Requirements

Room Temperature

7 days
Causes for Rejection
  • Nonpreserved feces
  • Transport media other than Cary-Blair or C and S,
  • Modified Cary-Blair
  • Visibly formed feces.
Methodology
Real-Time Polymerase Chain Reaction (Pcr)/Rna Probe Hybridization
Reference Intervals

 See patient report.

Limitations

A positive result suggests that norovirus is the cause of gastrointestinal disease (diarrhea or vomiting); however, in certain patients (eg, immunocompromised hosts), norovirus may be shed for weeks to months in the absence of symptoms.

This test should not be used as a test-of-cure, due to the fact that norovirus nucleic acid may be detected in patients for weeks to months following the resolution of symptoms.(2)

A negative result suggests that norovirus is not the cause of gastrointestinal disease (diarrhea or vomiting); however, viral nucleic acid may be present at a level that is below the limit of detection for this test. The results should be interpreted in the context of the patient's clinical presentation and other laboratory findings.

Alternate Names

 Norwalk Virus

Reference Lab
Mayo Clinic Laboratories
Testing Schedule
Routine, daily