Test Directory

• IgG and albumin quantitation in both serum and spinal fluid samples
• CSF, IgG
• CSF albumin ratio
• CSF IgG index
• CSF IgG synthesis rate
• Oligoclonal banding

Adjunct in aiding clinical diagnosis of multiple sclerosis

Specimen Type: Cerebrospinal Fluid AND Serum

Collection Container: Sterile, Non-Additive Container (CSF) AND Gold Top, Serum Separator; OR Red Top, Plain Tube

Desired Specimen Volume: 1.5 mL CSF AND 2 mL Serum

Test requires serum AND CSF collected at the same time.

Serum:

1. Collect specimen in gold top, serum separator tube via venipuncture.

CSF:

1. Collect cerebrospinal fluid via lumbar puncture.
2. Avoid contaminating CSF with blood.

Serum:

1. Separate serum from cells.
2. Transfer 2mL of serum into a clear aliquot tube (screw cap).

CSF:

1. Centrifuge CSF at 1500xg for 20 minutes.
2. Ensure that residual fibrin and cellular matter have been removed.
3. Transfer 1.5 mL of the CSF supernatant to a Sterile, Non-Additive aliquot tube.

Transport to the laboratory refrigerated. 

• Plasma instead of serum specimen
• Serum AND CSF NOT collected within eight hours of each other

See patient report.

• Multiple Sclerosis (MS) Profile
• MS Profile