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Test Code
PPOPI
Test Name
Opiates, Quantitative, Pain Management, Urine
CPT Codes
AMA 80361 CMS G0480
Expected Turnaround Time
1 - 5 days
Clinical Utility

Useful in determining the use or abuse of Opiates in urine compliance monitoring for pain management.

 

Testing includes identification and quantitation of:

  • Codeine
  • Hydrocodone
  • Hydromorphone
  • Morphine
  • Norhydrocodone
  • 6-Monoacetylmorphine
Specimen and Container Info

Preferred Specimen Type: Urine

Preferred Collection Container: Plastic Urine Container (Preservative Free)

Desired Specimen Volume: 10 mL
Processing and Submission Instructions
  • If using paper requisition, submit specimen with a completed Pain Management Drug Testing Request (HNL-56).
  • Interpretation is dependent on completing the prescribed medication history section at the bottom of the form.
  • List only the medications taken within the last 2-3 days.
Transport Instructions

Transport to the laboratory refrigerated.
Stability Requirements

Room Temperature

 7 Days

Refrigerated

7 Days 
Causes for Rejection

Urine specimens received in tubes containing preservatives will be rejected.
Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

Interpretation and concentration of drug/metabolite in urine is dependent on dose, time of dose, metabolic rate, and hydration state.
Limitations

Analyte

Cutoff Concentration (ng/mL)

Codeine

50

Hydrocodone

50

Hydromorphone

50

Morphine

50

Norhydrocodone

50

6-Monoacetylmorphine

5
Performing Location
Roble Road Core Laboratory
Alternate Names

 Codeine Alternate Names:

  • Tylenol with Codeine
  • Pyregesic-C
  • Tylenol No 3
  • Tylenol #3
  • Paracetamol and Codeine
  • Codeine

 

Morphine Alternate Names:

  • Arymo Er
  • Kadian
  • MS Contin
  • Morphabond
  • Oramorph SR
  • Roxanol
  • AVINza
  • Morphine

 

6MAM Alternate Names:

  • Heroin metabolite
  • Monoacetylmorphine
  • Acetylmorphine
  • 6MAM

 

Hydroocodone Alternate Names:

  • Vicodin
  • Lorcet
  • Zamicet
  • Xodol
  • Vicoprofen
  • Hydrocodone

 

Hydromorphone Alternate Names:

  • Dilaudid
  • Exalgo
  • Palladone
  • Hydromorphone
Testing Schedule
Routine, 5 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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