Test Directory

Test Code
TRIL
Test Name
Oxcarbazepine Metabolite, Serum
CPT Codes
80183
Expected Turnaround Time
3 - 5 days
Clinical Utility
  • Identification and quantitation of oxcarbazepine metabolite.
  • Useful for monitoring oxcarbazepine therapy and assessing compliance.
Specimen and Container Info

Preferred Specimen Type:  Serum

Preferred Collection Container: Red Top, Plain

Desired Specimen Volume: 1 mL

Collection Instructions

Collect at trough level, immediately prior to the next dose.

Processing and Submission Instructions
  1. Allow specimen to sit upright 30 minutes.
  2. Centrifuge for 5 minutes at 3000 rpm within 2 hours of collection.
  3. Transfer serum to plastic vial and refrigerate.
Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

48 hours

Refrigerated

14 days

Frozen

30 days

Causes for Rejection

Specimens collected in separator tubes will be rejected.  

Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

Analyte

Therapeutic Range (µg/mL)

Oxcarbazepine Metabolite (MHC)

3.0 - 35.0

 Note: The therapeutic range is based on concentrations of the metabolite (MHC) not the parent drug. This assay measures the metabolite only.

Performing Location
Roble Road Core Laboratory
Alternate Names
  • Trileptal
  • MHC
  • Oxcarbazepine
Testing Schedule
Routine, 3 times per week