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Test Code
PAI1P
Test Name
PAI-1 Gene Polymorphism
CPT Codes
81400
Expected Turnaround Time
7 - 11 days
Clinical Utility

Plasma plasminogen activator inhibitor, PAI-1 is a major inhibitor of fibrinolysis. The 4G variant (AF386492.2:g.837del) in the PAI-1 (Serpine 1) gene promoter region is associated with an increase in the level of PAI-1 in plasma. Increased levels of PAI-1 in plasma may increase the risk for arterial and venous thrombosis, myocardial infarction, and progression of atherosclerosis and also recurrent spontaneous abortion.
Specimen and Container Info

Specimen Type: Whole Blood

 

Collection Container: Yellow Top (ACD solution A or B)

Alternate Collection Container: Green Top (sodium or lithium heparin) or Lavender Top (EDTA)

 

Desired Specimen Volume: 5 mL
Collection Instructions
  1. Collect a pale-yellow top (ACD) tube via venipuncture.
Processing and Submission Instructions
  1. Transport 5 mL of whole blood in the original collection container.
Transport Instructions

Transport to the laboratory at room temperature.  
Stability Requirements

Room Temperature

8 days

Refrigerated

8 days
Methodology
Polymerase Chain Reaction (PCR)
Reference Intervals

See patient report.
Alternate Names
  • PAI-1 4G/5G Polymorphism
  • Plasminogen Activator Inhibitor-1 (PAI-1) 4G/5G
  • PAI-1 Promoter Polymorphism
  • Plasminogen Activator Inhibitor-1
Reference Lab
Quest Diagnostics Nichols Institute
Testing Schedule
Routine, 2 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
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