Test Directory

Test Code
PAI1
Test Name
Plasminogen Activator Inhibitor 1
CPT Codes
85415
Expected Turnaround Time
3 - 5 days
Specimen and Container Info

Specimen Type: Citrated Platelet-Poor Plasma

  

Collection Container: Light Blue Top (Sodium Citrate)

Desired Specimen Volume: 0.5 mL

Collection Instructions
  1. Collect a light blue top (sodium citrate) tube via venipuncture
  2. Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio.
  3. The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing of the anticoagulant with the blood.
  4. A discard tube is not required prior to collection of coagulation samples unless the sample is collected using a winged (butterfly) collection system. With a winged blood collection set a discard tube should be drawn first to account for the dead space of the tubing and prevent under-filling of the evacuated tube.
  5. When noncitrate tubes are collected for other tests, collect sterile and nonadditive (red-top) tubes prior to citrate (blue-top) tubes. Any tube containing an alternative anticoagulant should be collected after the blue-top tube. Gel-barrier tubes and serum tubes with clot initiators should also be collected after the citrate tubes.
Processing and Submission Instructions

Platelet-Poor Plasma Processing Instructions

  1. Perform platelet-poor plasma procedure
  2. Transfer 0.5 mL of platelet-poor plasma to a LabCorp PP transpak frozen tube.
  3. Freeze immediately and maintain frozen until tested.
  4. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Transport Instructions

Transport to the laboratory frozen. 

Stability Requirements

Frozen

11 days

Causes for Rejection
  • Specimen received unfrozen
  • Noncitrated plasma specimen
Methodology
ELISA
Reference Intervals

 See patient report.

Limitations

PAI-1 is a acute-phase reactant and can become transiently elevated by infection, inflammation, or trauma. PAI-1 levels increase during pregnancy.

Alternate Names
  • Plasminogen Activator Inhibitor 1 (PAI-1) Activity
  • PAI-1
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, 3 times per week