Test Directory

Test Code
PORRU
Test Name
Porphyrins, Fractionated, Quantitative, Random Ur
CPT Codes
84120
Included Tests
  • Coproporphyrin I
  • Coproporphyrin III
  • Heptacarboxyporphyrin
  • Hexacarboxyporphyrin
  • Pentacarboxyporphyrin
  • Uroporphyrin I
  • Uroporphyrin III
  • Total Porphyrins
Expected Turnaround Time
5 - 7 days
Clinical Utility

Porphyria is a group of distinct disorders, characterized by the abnormal accumulation of porphyrins or porphyrin precursors. Porphyrin fractionation of urine is useful in diagnosing porphyrin cutanea tarda, hereditary coproporphyria, and variegate porphyria.

Specimen and Container Info

Specimen Type: Random Urine Protected from Light

Collection Container: Plastic Urine Container (Preservative Free)

Desired Specimen Volume: 2 mL

Collection Instructions
  1. Collect random urine in a plastic urine container (preservative free).
  2. Protect specimen from light and maintain refrigerated.
Processing and Submission Instructions
  1. Transfer 2 mL of urine to an amber aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Refrigerated

7 days

Frozen

30 days

Causes for Rejection
  • Samples not protected from light 
  • Samples with a pH <4.0
Methodology
High Performance Liquid Chromatography (HPLC)
Reference Intervals

See patient report.

Reference Lab
Quest Diagnostics Nichols Institute
Testing Schedule
Routine, 5 times per week