Test Directory

Test Code
PYKIN
Test Name
Pyruvate Kinase
CPT Codes
84220
Expected Turnaround Time
2 - 3 days
Clinical Utility
Preferred initial screening test for pyruvate kinase deficiency.
Specimen and Container Info

Specimen Type: Whole Blood

Collection Container: Lavender Top (EDTA)

Alternate Collection Container: Green Top (Sodium or Lithium Heparin), Pale Yellow Top (ACD Solution A or B) or Pink Top (EDTA)

Desired Specimen Volume: 1 mL

Collection Instructions
  1. Collect a lavender top (EDTA) tube via venipuncture
Processing and Submission Instructions
  1. Transport 1 mL of whole blood in the original collection container.
Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Refrigerated

20 days
Methodology
Quantitative Enzymatic Assay
Reference Intervals

See patient report.

Limitations

Patients who have recently received transfusions have normal donor cells that may mask PK deficient erythrocytes.

Alternate Names
  • PK
  • Pyruvate Kinase (RBC)
Reference Lab
ARUP Laboratories
Testing Schedule
Routine, daily