Test Directory

Test Code
QUETP
Test Name
Quetiapine, Quantitative, Whole Blood
CPT Codes
AMA 80342, CMS G0480
Expected Turnaround Time
5 - 7 days
Clinical Utility

Quetiapine is a neuroleptic agent used in the treatment of psychosis. Although routine therapeutic drug monitoring is not indicated, drug levels may be used to identify noncompliance and/or toxicity.

Useful in determining the use or abuse of Quetiapine.

Testing includes identification and quantitation of:

  • Quetiapine
Specimen and Container Info

Specimen

Container

Volume

Whole Blood

Grey Top* (Sodium Fluoride, Potassium Oxalate)

3 mL

Whole Blood

Dark Green Top (Lithium Heparin)

3 mL

Whole Blood

Lavender Top (EDTA)

3 mL

Serum

Red Top, Plain

1 mL

*Preferred Specimen

Processing and Submission Instructions

For forensic or legal purposes, submit specimen in a plastic evidence bag with a Chain-of-Custody Form.

Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Room Temperature

7 days

Refrigerated

 7 days

Causes for Rejection

Specimens collected in separator tubes will be rejected.

Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

Expected steady state levels in patients receiving recommended daily dose:

  • 100-1000 ng/mL
Limitations

Analyte

Reporting Limit (ng/mL)

Quetiapine

25

Performing Location
Roble Road Core Laboratory
Alternate Names
  • Seroquel
Testing Schedule
Routine, 2 times per week