Test Directory

Test Code
RBCB3
Test Name
RBC Band 3 Protein Reduction
CPT Codes
88184
Expected Turnaround Time
4 - 8 days
Clinical Utility
Use to confirm diagnosis of hereditary spherocytosis when hemolytic anemia and spherocytes are present.
Specimen and Container Info

Specimen Type: Whole Blood

Collection Container: Lavender Top (EDTA)

Alternate Collection Container: Green Top (Sodium or Lithium Heparin)

Desired Specimen Volume: 4 mL

Collection Instructions
  1. Collect a lavender top (EDTA) tube via venipuncture.
Processing and Submission Instructions
  1. Transport 4 mL of whole blood in the original collection container.
  2. Specimens must be analyzed within 7 days of collection.
Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

3 days

Refrigerated

7 days
Causes for Rejection
  • Clotted or hemolyzed specimen
  • Specimen older than 7 days
Methodology
Qualitative Flow Cytometry
Reference Intervals

 See patient report.

Alternate Names
  • Hereditary Spherocytosis, EMA, BAND 3, Osmotic Fragility
  • HS hemolytic anema assay
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, daily