Test Directory

Clear All
Test Code
S100B
Test Name
S-100B Protein, Serum
CPT Codes
86316
Expected Turnaround Time
1 - 8 days
Clinical Utility
Useful as a biomarker of various CNS pathologies and as a tumor marker for malignant melanoma.
Specimen and Container Info

Specimen Type: Serum

Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 2 mL
Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
  2. Allow specimen to clot at room temperature
Processing and Submission Instructions
  1. Separate serum from cells ASAP or within 2 hours of collection.
  2. Transfer 2 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory frozen.
Stability Requirements

Room Temperature

24 hours (after separation from cells)

Refrigerated

7 days (after separation from cells)

Frozen

3 months (after separation from cells)
Methodology
Quantitative Enzyme-Linked Immunosorbent Assay
Reference Intervals

See patient report.
Limitations

This assay is performed using the CanAg® S100 Enzyme Immunoassay. Results obtained with different assay methods or kits cannot be used interchangeably. Results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.
Reference Lab
ARUP Laboratories
Testing Schedule
Routine, 1 time per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
© 2026 HNL Lab Medicine. All rights reserved.