Test Directory

Test Code
SCL7B
Test Name
Scl-70 Autoantibody
CPT Codes
86235
Included Tests

Scl-70 Autoantibody.

Expected Turnaround Time
4 - 7 days
Clinical Utility

Scl 70 antibodies are found in about 20% of patients with scleroderma, especially those with more progressive forms of the disease. They are also found in 10–18% of cases of CREST syndrome, a limited form of scleroderma.

Specimen and Container Info

Preferred Specimen Type: Serum

Minimum Acceptable Volume: 2 mL

Preferred Collection Container: Gold Top, Serum Separator

Processing and Submission Instructions

Separator tubes: Contains clot activator and gel for separating serum from cells, but not anticoagulant. Separate serum from cells as soon as the clot has formed (30 minutes). If specimen is centrifuged before clotting is complete, a fibrin clot will form on top of the cell. This may cause the gel barrier to not be intact and could cause improper separation of serum and cells, possibly affecting test results.

Transport Instructions

Transport refrigerated.

Stability Requirements

Refrigerated

7 days

Frozen

<20°C for long-term storage.

Freeze/Thaw Cycles

Avoid multiple freeze-thaw cycles.

Methodology
Bead-Based Multiplex Immunoassay
Reference Intervals

<1.0 AI, Negative

Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, Monday - Friday no holidays