Test Directory

Test Code
SRASY
Test Name
SEROTONIN RELEASE ASSAY
CPT Codes
82542
Included Tests
  • SRA, Low Dose Heparin
  • SRA, High Dose Heparin
Expected Turnaround Time
3 - 7 days
Clinical Utility

Confirmatory assay used in the evaluation of heparin-induced thrombocytopenia (HIT).

Specimen and Container Info

Specimen Type: Serum

 

Collection Container: Gold Top, Serum Separator 

Alternate Collection Container: Red Top, Plain

 

Desired Specimen Volume: 1 mL


Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 1 mL of serum to a LabCorp pp transpak frozen purple tube.
  3.  To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Transport Instructions

Transport to the laboratory frozen.

Stability Requirements

Frozen

14 days

Causes for Rejection
  • Room temperature specimen received
  • Grossly hemolyzed, icteric, and lipemic samples
Methodology
Liquid Chromatography - Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

See patient report.

Limitations

The diagnosis of heparin-induced thrombocytopenia should not be based entirely on the results of the Heparin-dependent Platelet Antibody assay and should take into account the results of the immunologic HIT assay, presence and timing of thrombocytopenia in relation to heparin administration, the presence of thrombosis or other HIT-related sequelae, as well as determination of other causes of thrombosis.

Alternate Names
  • Functional HIT Assay
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Monday-Friday