Test Directory

Test Code
SEXHB
Test Name
Sex Hormone Binding Globulin
CPT Codes
84270
Expected Turnaround Time
1 day
Clinical Utility
Levels of SHBG are under the positive control of estrogens and thyroid hormones, and are suppressed by androgens. Decreased levels of SHBG are frequently seen in hirsutism, virilization, obese postmenopausal women, and in women with diffuse hair loss. Increased levels may be present in cases of hyperthyroidism, testicular feminization, cirrhosis, male hypogonadism, pregnancy, women using oral contraceptives, and prepubertal children.
Specimen and Container Info

Specimen Type: Serum

Preferred Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Separator

Minimum Acceptable Volume: 0.8 mL

Processing and Submission Instructions

Separator tubes: Contains clot activator and gel for separating serum from cells, but not anticoagulant. Separate serum from cells as soon as the clot has formed (30 minutes). If specimen is centrifuged before clotting is complete, a fibrin clot will form on top of the cell. This may cause the gel barrier to not be intact and could cause improper separation of serum and cells, possibly affecting test results.

Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Refrigerated

7 Days
Methodology
Chemiluminescent Immunoassay
Reference Intervals
Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, daily