Test Directory

SRP is considered a Myositis-specific antibody. It is commonly found in Polymyositis, ILD and arthritis, and occasionally in dermatomyositis. Anti-SRP was first described in a polymyositis patient in 1986. Anti-SRP antibodies are rare, in only about 4% of myositis patients, and are often found in African American females with an acute, severe onset of polymyositis, with poor response to therapy.

Specimen Type: Serum

Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 1 mL

1. Collect a gold top, serum separator tube via venipuncture.

1. Separate serum from cells within one hour of collection.
2. Transfer 1 mL of serum to a clear aliquot tube (screw cap).

Transport to the laboratory refrigerated. 

• Grossly hemolyzed
• Bacterial contamination
• Lipemic specimen
• Icteric specimen
• Non-serum specimen types

 See patient report.

• Anti-SRP Ab (RDL)
• Signal Recognition particle, SRP