Test Directory

Test Code
SIROL
Test Name
Sirolimus
CPT Codes
80195
Expected Turnaround Time
1 day
Clinical Utility
Immunosuppressant drug used for treatment of rejection following transplantation.
Specimen and Container Info

Specimen Type: Whole Blood

Preferred Collection Container: Lavender Top (EDTA) 

Minimum Acceptable Volume: 0.9 mL

Processing and Submission Instructions

Tubes with anticoagulant: To ensure accurate test results, all tubes containing an anticoagulant or preservative must be allowed to fill completely. Attempts to force more blood into the tube by exerting pressure, as in collection with a syringe, will result in damage to the red cells (hemolysis).

Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Room Temperature

24 hours

Refrigerated

7 days

Frozen

3 months

Methodology
Enzyme Immunoassay
Reference Intervals
Methodology: Emit Immunoassay

No optimal therapeutic range for sirolimus has been established. Optimal ranges depend on various factors, including the time post-transplant, comedications used, the risk of rejection, and the organ transplanted. Consistent use of one assay is recommended as values vary amongst methodologies.
Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, daily