Test Directory

Includes serotypes 1, 3, 4, 5, 8, 9 (9N), 12 (12F), 14, 19 (19F), 23 (23F), 26 (6B), 51 (7F), 56 (18C), 68 (9V).

This test is used to estimate pre-existing antibody levels for different pneumococcal serotypes and to assess immunologic responses after pneumococcal vaccination. Responses to pneumococcal conjugate vaccines are demonstrated by 2- to 4-fold increases in type-specific IgG levels.

Specimen Type: Serum

Preferred Collection Container: Red Top, Plain

Alternate Collection Container: Gold Top, Serum Separator

Desired Specimen Volume: 0.5 mL

1. Collect a red top, plain tube via venipuncture.

If PRE and POST vaccination testing is desired, please follow these instructions:

1. PRE and POST samples should be tested together on the same run to avoid variation in results caused by lot to lot and inter assay variation.
2. It is recommended that two PRE tubes be drawn. Save one PRE serum frozen. The other can be sent to determine the need to vaccinate.
3.  If patient already has protective values, there is no need to revaccinate and test a POST sample. If PRE results do not show protective values, send the saved PRE sample together with the POST vaccination sample.

1. Separate serum from cells.
2. Transfer 0.5 mL of serum to a clear aliquot tube (screw cap).

Transport to the laboratory refrigerated. 

See patient report.

• Streptococcus pneumoniae Antibody (IgG) (14 Serotypes), MAID