Test Directory

Test Code
STM
Test Name
Striated Muscle Antibody, IgG Profile
CPT Codes
86255
Included Tests
STRIATED MUSCLE ANTIBODY IgG SCREEN
Expected Turnaround Time
1 - 4 days
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
Reference Intervals

Less than 1:40

When detected in the presence of acetylcholine receptor (AChR) antibody, striated muscle antibodies, which bind in a cross-striational pattern to skeletal and heart muscle tissue sections, are associated with late-onset myasthenia gravis (MG). Striated muscle antibodies recognize epitopes on three major muscle proteins, including: titin, ryanodine receptor (RyR) and Kv1.4 (an alpha subunit of voltage-gated potassium channel [VGKC]). Isolated cases of striated muscle antibodies may be seen in patients with certain autoimmune diseases, rheumatic fever, myocardial infarction, and following some cardiotomy procedures.

Reference Lab
ARUP Laboratories
Testing Schedule
Routine, 6 times per week