Test Directory

Test Code
TCRUZ
Test Name
T. cruzi Ab, IgG Panel
CPT Codes
86753 X 2
Included Tests
  • T. cruzi Antibody IgG
  • T. cruzi, Recombinant Ag.
Expected Turnaround Time
4 - 10 days
Clinical Utility

Aid in the diagnosis of exposure and chronic phase Chagas disease (T. cruzi).

Specimen and Container Info

Specimen Type: Serum

 

Collection Container: Red Top, Plain

Alternate Collection Container: Gold Top, Serum Separator

 

Desired Specimen Volume: 0.5 mL

Collection Instructions
  1. Collect a red top, plain tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells within 2 hours of collection.
  2. Transfer 0.5 mL of serum to a clear aliquot tube (screw cap).
Patient Preparation

Parallel testing is preferred and convalescent specimens must be received within 30 days of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Room Temperature

48 hours

Refrigerated

14 days

Frozen

1 year

Causes for Rejection
  • Plasma
  • Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens
Methodology
ELISA
Reference Intervals

See patient report.

Limitations

According to the CDC, at least two different serologic tests should be used to make the laboratory diagnosis of chronic Chagas Disease, as no single serologic test is sufficiently sensitive and specific. If results between the two assays are discrepant, repeat testing or testing by a third method may be helpful.

This assay should not be used for blood donor screening or associated re-entry protocols, or for screening Human Cell and Cellular Tissue-Based Products (HCT/Ps).

Alternate Names
  • Chagas Antibody, IgG
  • Chagas disease
  • Trypanosomiasis
  • Trypanosoma cruzi Antibody, IgG Panel
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, 3 times per week