Test Directory

Test Code
TACRO
Test Name
Tacrolimus
CPT Codes
80197
Expected Turnaround Time
1 day
Clinical Utility
Immunosuppressant drug used for treatment of rejection following transplantation.
Specimen and Container Info

Specimen Type: Whole Blood

Preferred Collection Container: Lavender Top (EDTA) 

Minimum Acceptable Volume: 0.4 mL

Processing and Submission Instructions

Tubes with anticoagulant: To ensure accurate test results, all tubes containing an anticoagulant or preservative must be allowed to fill completely. Attempts to force more blood into the tube by exerting pressure, as in collection with a syringe, will result in damage to the red cells (hemolysis).

Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Refrigerated

7 days

Frozen

1 month

Freeze/Thaw Cycles

Avoid repeated freezing and thawing.

Methodology
Fixed
Reference Intervals
Methodology: QMS Immunoassay

No optimal therapeutic range for tacrolimus has been established. Optimal ranges depend on various factors, including the time post-transplant, comedications used, the risk of rejection, and the organ transplanted. Consistent use of one assay is recommended as values vary amongst methodologies.
Performing Location
Roble Road Core Laboratory
Testing Schedule
Routine, daily