Test Directory

Test Code
THTO
Test Name
Th/To Antibody
CPT Codes
83516
Expected Turnaround Time
14 - 21 days
Clinical Utility
The Th/To antibodies are present in 10-19% of patients with limited SSc, in 11% of patients with diffuse cutaneous SSc, and in 3% of patients with primary Raynaud's disease. Anti-Th/To antibody has been shown to be highly specific for patients with SSc.
Specimen and Container Info

Specimen Type: Serum

  

Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 1 mL

Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells within one hour of collection.
  2. Transfer 1 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

7 days

Refrigerated

14 days

Frozen

60 days

Freeze/Thaw Cycles

Stable x1

Causes for Rejection
  • Grossly hemolyzed
  • Bacterial contamination
  • Lipemic specimen
  • Icteric specimen
  • Non-serum specimen types
Methodology
RIPA gel radiography
Reference Intervals

Negative.

Alternate Names
  • Anti-Th/To Ab (RDL)
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Varies