Test Directory

Test Code
THTO
Test Name
Th/To Antibody
CPT Codes
83516
Expected Turnaround Time
14 - 21 days
Clinical Utility
The Th/To antibodies are present in 10-19% of patients with limited SSc, in 11% of patients with diffuse cutaneous SSc, and in 3% of patients with primary Raynaud's disease. Anti-Th/To antibody has been shown to be highly specific for patients with SSc.
Specimen and Container Info

Preferred Specimen Type: Serum

  

Preferred Collection Container: Gold Top, Serum Separator

Desired Specimen Volume: 1 mL

Collection Instructions

Collect specimen in gold top, serum separator tube via venipuncture. Centrifuge and transfer serum into plastic aliquot tube.

Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

7 days

Refrigerated

14 days

Frozen

60 days

Freeze/Thaw Cycles

1
Causes for Rejection
Grossly hemolyzed; bacterial contamination; lipemic specimen; icteric specimen; non-serum specimen types
Methodology
RIPA gel radiography
Reference Intervals

Negative.

Reference Lab
Labcorp Of America Holdings