Test Directory

Test Code
TRINH
Test Name
Thrombotic Risk, Inherited
CPT Codes
81240, 81241, 85300, 85303, 85306
Included Tests
  • Factor V Leiden R506Q Mutation
  • Prothrombin (G20210A) Mutation
  • Antithrombin III Activity
  • Protein C, Functional
  • Protein S, Functional
Expected Turnaround Time
2 - 4 days
Clinical Utility

See individual test listings.

Specimen and Container Info

Specimen Type: Plasma and Whole Blood

Collection Container: 2 Full Light Blue Top (Sodium Citrate) and 1 Lavender Top (EDTA)

Minimum Volume: 1 mL plasma from 1 Light Blue Top (Sodium Citrate) and 500 µL whole blood from Lavender Top (EDTA)

Collection Instructions

Plasma: Blood should be collected in a blue-top tube containing 3.2% buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood-to-anticoagulant ratio.

Processing and Submission Instructions

Create platelet poor plasma within 4 hours of collection according to the Specimen Collection and Processing Guidelines for Coagulation Testing.

Patient Preparation
Testing is contradictory for patients on anticoagulant therapy.
Transport Instructions

Platelet poor plasma: Transport to the laboratory frozen. 

Whole Blood: Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

Plasma: 4 hours

Whole blood: 24 Hours

Refrigerated

Whole blood: 15 Days

Frozen

Platelet poor plasma: 14 days

Whole blood: 3 Months

Causes for Rejection
  • Any specimen with leakage on the outside of the container will be rejected
  • Any specimen collected in an outdated collection tube will be rejected
  • Platelet poor plasma thawed in transit
  • Specimens past stability
Methodology
See Individual Test Listing
Reference Intervals

See Indvidual Test Listings.

Performing Location
Roble Road Core Laboratory
Alternate Names
  • Hypercoagulability Profile
Testing Schedule
Routine, 2 times per week