Test Directory

Test Code
TOXO
Test Name
Toxocara Antibody by ELISA
CPT Codes
86682
Expected Turnaround Time
4 - 8 days
Clinical Utility

Aids in the diagnosis of Toxocara infection.

Specimen and Container Info

Specimen Type: Serum

  

Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 0.5 mL

Collection Instructions
  1. Collect a gold top, serum separator tube via venipuncture.
Processing and Submission Instructions
  1. Separate serum from cells.
  2. Transfer 0.5 mL of serum to a clear aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory frozen. 

Stability Requirements

Refrigerated

5 days

Frozen

30 days

Causes for Rejection
  • Gross hemolysis
  • Gross lipemia
  • Heat-inactivated
Methodology
ELISA
Reference Intervals

See patient report.

Limitations

A single negative result does not rule out infection. Assay sensitivity may be decreased depending on the site of infection, in cases of low parasitic burden, and timing of sample collection relative to exposure. In ocular toxocariasis, Toxocara antibody levels in serum can be low or absent despite clinical disease. Repeat testing should be considered in patients who are at high risk of exposure or infection.

False-negative results may occur in severely immunosuppressed patients.

Positive results should be interpreted with patient's clinical status and exposure history.

Positive results by this assay do not distinguish acute versus remote infection.

False-positive results may occur in patients with other helminth infections.

This assay uses synthetic antigens derived from Toxocara canis. Studies evaluating the sensitivity of this assay in patients infected with Toxocara cati have not been performed.

Alternate Names
  • Ocular toxocariasis
  • TOXOC
  • Toxocara canis
  • Toxocariasis
  • Visceral toxocariasis
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, 2 times per week