Test Directory

Clear All
Test Code
TRAZO
Test Name
Trazodone, Quantitative, Whole Blood
CPT Codes
AMA 80338, CMS G0480
Expected Turnaround Time
5 - 7 days
Clinical Utility

Trazodone is used to treat depression. This test may be used to monitor compliance or adjust dosage to achieve optimal therapeutic concentrations.

Useful in determining the use or abuse of Trazodone.

Testing includes identification and quantitation of:

  • Trazodone
  • mCPP (Trazodone Metabolite)
Specimen and Container Info

Specimen

Container

Volume

Whole Blood

Grey Top* (Sodium Fluoride, Potassium Oxalate)

3 mL

Whole Blood

Dark Green Top (Lithium Heparin)

3 mL

Whole Blood

Lavender Top (EDTA)

3 mL

Serum

Red Top, Plain

1 mL

*Preferred Specimen
Processing and Submission Instructions

For forensic or legal purposes, submit specimen in a plastic evidence bag with a Chain-of-Custody Form.
Transport Instructions

Transport to the laboratory refrigerated.
Stability Requirements

Room Temperature

 7 days

Refrigerated

 7 days
Causes for Rejection

Specimens collected in separator tubes will be rejected. 
Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

 Analyte

Therapeutic Range (ng/mL)

Trazodone

500-1100

mCPP (trazodone metabolite)

Not established
Limitations

Analyte

Reporting Limit (ng/mL)

Trazodone

25

mCPP (trazodone metabolite)

25
Performing Location
Roble Road Core Laboratory
Alternate Names
  • Desyrel
  • Oleptro
Testing Schedule
Routine, 2 times per week
The American Medical Association (AMA) Current Procedural Terminology (CPT) codes published by HNL Lab Medicine are guidelines and are intended for informational purposes only. CPT coding is the exclusive responsibility of the billing entity. View the Terms.
© 2026 HNL Lab Medicine. All rights reserved.