Test Directory

Test Code
TRDNA
Test Name
Trofile DNA
CPT Codes
87999
Expected Turnaround Time
29 - 33 days
Clinical Utility
Detect HIV-1 coreceptor tropism; determine eligibility for CCR5 antagonist therapy such as Selzentry™ (maraviroc).
Specimen and Container Info

Specimen Type: Whole Blood

  

Collection Container: Lavender Top (EDTA)

Desired Specimen Volume: 4 mL

Collection Instructions
  1. Collect 2 lavender top (EDTA) tubes via venipuncture.
  2. Freeze immediately after collection.
Processing and Submission Instructions
  1. Transport 4 mL of frozen whole blood in the original collection containers.
Patient Preparation

This procedure should be used for patients with documented HIV-1 infection and undetectable viral loads.

Transport Instructions

Transport to the laboratory frozen. 

Stability Requirements

Frozen

-20° C = 14 days

-80° C = indefinite

Causes for Rejection
  • Heparinized plasma
  • Nonfrozen specimen
Methodology
Polymerase Chain Reaction Amplification and Viral Culture
Reference Intervals

 See patient report.

Alternate Names
  •  Human Immunodeficiency Virus 1 (HIV-1) Trofile® DNA (Monogram® Coreceptor Tropism), Whole Blood
Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, daily