Test Directory

Test Code
TROFI
Test Name
Trofile
CPT Codes
87999
Expected Turnaround Time
27 - 35 days
Clinical Utility

Detect HIV-1 coreceptor tropism; determine eligibility for CCR5 antagonist therapy such as maraviroc (Selzentry®)

Specimen and Container Info

Preferred Specimen Type: Plasma

  

Preferred Collection Container: Lavender Top (EDTA)

Alternate Collection Container: White Top (EDTA)

Desired Specimen Volume: 3 mL

Collection Instructions

Collect specimen in four lavender top (EDTA) tubes or two white top tubes (plasma preparation tubes) via venipuncture. Centrifuge and transfer plasma to plastic aliquot tubes and freeze.

Transport Instructions

Transport to the laboratory frozen. 

Causes for Rejection
 PPT™ not centrifuged; insufficient volume; heparinized plasma; nonfrozen specimen
Methodology
Polymerase Chain Reaction Amplification and Viral Culture
Reference Intervals

 See patient report.

Limitations

This procedure should be used for patients with documented HIV-1 infection and viral loads ≥1000 copies/mL.

Reference Lab
Labcorp Of America Holdings