Test Directory

Test Code
VITC
Test Name
Vitamin C
CPT Codes
82180
Expected Turnaround Time
3 - 5 days
Clinical Utility

Along with dietary history, evaluating serum ascorbic acid levels should be considered for patients with classic signs and symptoms of scurvy, as well as for those with common, nonspecific, chronic musculoskeletal complaints. Vitamin C deficiency is generally defined as plasma or serum concentrations less than 0.2 mg/dL, or the the level at which signs and symptoms of scurvy may appear. Serum ascorbic acid concentrations between 0.2 and 0.4 mg/dl are considered low.

Specimen and Container Info

Specimen Type: Plasma

  

Collection Container: Dark Green Top (Lithium Heparin)  

Desired Specimen Volume: 1 mL

Collection Instructions
  • Collect specimen in dark green top, lithium heparin tube via venipuncture.
  • Mix immediately by gentle inversion at least six times to ensure adequate mixing.
Processing and Submission Instructions
  1. Separate plasma from cells immediately after collection.
  2. Transfer 1 mL of plasma to a light-protected amber aliquot tube.
  3. Separated plasma must be placed on dry ice for shipment within 4 hours of separation.
  4. To avoid delays in turnaround time when requesting multiple tests on frozen samples, please submit separate frozen specimens for each test requested.
Transport Instructions

Transport to the laboratory frozen. 

Stability Requirements

Frozen

14 days

Freeze/Thaw Cycles

Stable x1

Causes for Rejection
  • Anticoagulants other than Lithium Heparin
  • Specimen not protected from light
Methodology
Liquid Chromatography - Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

0.4–2.0 mg/dL

Reference Lab
Labcorp Of America Holdings
Testing Schedule
Routine, 6 times per week