Test Directory

Test Code
WNASF
Test Name
West Nile Virus Antibody, IgG and IgM, Cerebrospinal Fluid
CPT Codes
86788, 86789
Included Tests
  • West Nile Virus Antibody, IgG, Cerebrospinal Fluid
  • West Nile Virus Antibody, IgM, Cerebrospinal Fluid
Expected Turnaround Time
1 - 4 days
Clinical Utility

Aiding in diagnosis of central nervous system infection with West Nile virus.

Specimen and Container Info

Specimen Type: Cerebrospinal Fluid

 

Collection Container: Sterile, Non-additive Container (CSF) 

Desired Specimen Volume: 1 mL

Collection Instructions
  1. Collect CSF specimen via lumbar puncture.
Processing and Submission Instructions
  1. Submit specimen from collection vial 2, 3, or 4.
  2. Transfer 1 mL of CSF to a sterile aliquot tube (screw cap).
Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Refrigerated

7 days

Frozen

30 days
Causes for Rejection
  • Gross hemolysis
Methodology
Enzyme Linked Immunosorbent Asasy (Elisa)
Reference Intervals

See patient report.

Limitations

Test results should be used in conjunction with clinical evaluation, exposure history, and other available diagnostic procedures. The significance of negative test results in immunosuppressed patients is uncertain. False-positive results may occur in patients infected with other flaviviruses, including dengue virus, St. Louis virus, and Zika virus and in persons previously infected with West Nile virus (WNV).

WNV antibody results for spinal fluid (CSF) should be interpreted with caution. Complicating factors include low antibody levels found in CSF, passive transfer of antibody from blood, and contamination via a traumatic lumbar puncture.

Alternate Names
  • Arbovirus
  • Flavivirus
  • Mosquito borne encephalitis
  • Viral encephalitis
  • West Nile virus (WNV)
Reference Lab
Mayo Clinic Laboratories
Testing Schedule
Routine, 3 times per week