Test Directory

Test Code
YOCSF
Test Name
Yo Autoantibody, Cerebrospinal Fluid
CPT Codes
83520
Included Tests
Yo AUTOANTIBODY
Expected Turnaround Time
3 - 5 days
Clinical Utility

Purkinje cell (Yo) antibody is mainly found in patients with paraneoplastic cerebellar degeneration and is associated with breast, ovarian, and other gynecologic cancers. Some patients with ovarian cancer have low titers of Yo antibodies in the absence of cerebellar degeneration. This semi-quantitative assay may be useful in monitoring therapeutic responses in select cases.

Specimen and Container Info

Specimen Type: Cerebrospinal Fluid


Collection Container: Sterile, Non-additive Container (CSF) 


Desired Specimen Volume: 2 mL

Collection Instructions
  1. Collect cerebrospinal fluid (CSF) specimen via lumbar puncture.
Processing and Submission Instructions
  1.  Transfer 2 mL of CSF to a sterile aliquot tube (screw capped).
Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

72 hours

Refrigerated

28 days

Frozen

28 days
Methodology
Automated Nanoliter Scale Immunoassay
Reference Intervals

See patient report.

Alternate Names
  • Recombx® Yo Autoantibody Test
Reference Lab
Athena
Testing Schedule
Varies