Test Directory

Test Code
YOAA
Test Name
Yo Autoantibody, Serum
CPT Codes
83520
Expected Turnaround Time
3 - 5 days
Clinical Utility

Purkinje cell (Yo) antibody is mainly found in patients with paraneoplastic cerebellar degeneration and is associated with breast, ovarian, and other gynecologic cancers. Some patients with ovarian cancer have low titers of Yo antibodies in the absence of cerebellar degeneration. This semi-quantitative assay may be useful in monitoring therapeutic responses in select cases.

Specimen and Container Info

Preferred Specimen Type: Serum

  

Preferred Collection Container: Gold Top, Serum Separator

Alternate Collection Container: Red Top, Plain

Desired Specimen Volume: 2 mL

Collection Instructions

Collect specimen in gold top, serum separator tube or red top, plain tube via venipuncture. Centrifuge and transfer serum to aliquot tube.

Transport Instructions

Transport to the laboratory refrigerated. 

Stability Requirements

Room Temperature

72 hours

Refrigerated

28 days

Frozen

28 days
Methodology
Automated Nanoliter Scale Immunoassay
Reference Intervals

 <1:200

Reference Lab
Athena
Testing Schedule
Varies