Test Directory

Test Code
PPZOL
Test Name
Zolpidem, Quantitative, Pain Management, Urine
CPT Codes
AMA 80368, CMS G0480
Expected Turnaround Time
1 - 5 days
Clinical Utility

Useful in determining the use or abuse of Zolpidem in urine compliance monitoring for pain management.

 

Testing includes identification and quantitation of:

  • Carboxyzolpidem (Zolpidem metabolite)
Specimen and Container Info

Preferred Specimen Type: Urine

Preferred Collection Container: Plastic Urine Container (Preservative Free)

Desired Specimen Volume: 10 mL

Processing and Submission Instructions
  • If using paper requisition, submit specimen with a completed Pain Management Drug Testing Request (HNL-56).
  • Interpretation is dependent on completing the prescribed medication history section at the bottom of the form.
  • List only the medications taken within the last 2-3 days
Transport Instructions

Transport to the laboratory refrigerated.

Stability Requirements

Room Temperature

 7 Days

Refrigerated

 7 Days

Causes for Rejection

Urine specimens received in tubes containing preservatives will be rejected.

Methodology
Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Reference Intervals

Interpretation and concentration of drug/metabolite in urine is dependent on dose, time of dose, metabolic rate, and hydration state.

Limitations

Analyte

Cutoff Concentration (ng/mL)

Carboxyzolpidem

25

Performing Location
Roble Road Core Laboratory
Alternate Names
  • Ambien
  • Edluar
  • Intermezzo
  • Zolpimist
Testing Schedule
Routine, 5 times per week